Fourier 80

Advance your analytical capabilities and strengthen your curriculum with high-performance NMR in an easy-to-use, compact benchtop system. Tackle the challenges. Remove the barriers. Advance discovery.

Fourier 80

Highlights

Cryogen-free

The Fourier 80 can be installed in the fume hood or on the bench without the need for new infrastructure, providing easy maintenance and minimal cost of ownership.

80 MHz

The Fourier has been designed for the highest data quality and stability at 80 MHz, with excellent lineshape, resolution and sensitivity.

Flexibility

Adjustable temperature for the Fourier 80 allows samples to be measured from 25°C up to 60°C

Precision

Fourier 80 HD: Designed for performing complex molecular structure analysis mimicking high field NMR resolution

The Fourier 80 is an 80 MHz high-performance nuclear magnetic resonance (NMR) benchtop spectrometer designed for the routine laboratory in either research facilities or university settings.

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Features

See the Fourier 80 in action!

See how the Fourier 80 can be used in labs with high-field systems to maximize productivity.

Adjustable Temperature for Fourier 80

Fourier 80 Benefits

Compact footprint, designed for the routine laboratory use
Easy maintenance and minimal cost of ownership
Perform complex molecular analysis
Provides higher sample throughput
Optimized synthesis and process control directly on the bench
Automated data interpretation
Use Bruker high-field system workflows on the benchtop
Suitable for comprehensive range of applications
Reduces errors and maximizes efficiency

Technical Features

80-MHz high performance, cryogen-free permanent magnet
Superior spectral quality for precise results
Automation for up to 120 samples
Adjustable temperature (25-60°C)
On-line reaction monitoring with patented temperature-controlled transfer lines and controlled reaction path
Pulsed field gradient
Full flexibility with use of TopSpin software
GoScan software provides pre-defined, dedicated workflows
Push-button operation

Applications

Structure verification
Process optimization & control
Academic/Basic Research and advance discovery
Forensics and narcotics profiling
Authenticity and quality analysis of olive oil
Quantification of ethanol content in hand-sanitizers
For hands-on training in colleges and universities

Applications

Education for EduLab

Science students should learn a wide range of analytical techniques, but the infrastructure and maintenance needs of full-blown Nuclear Magnetic Resonance (NMR) and Electron Spin Resonance (ESR) spectrometers can limit access. So, Bruker has created special editions of FT-NMR and microESR benchtop instruments for colleges and universities to be used for a wide range of experiments in a teaching laboratory.

Automated Identification and Quantification with Benchtop NMR

The Advanced Chemical Profiling Software offers a truly automated, end-to-end workflow from sample to actionable information, adds significant value to high throughput environments such as production-linked labs, analytical testing services, R&D centers, and pilot-upscaling support functions within centers of excellence.

Reaction Monitoring for RxnLab and RxnLite

Designed for the analysis of chemical and bioprocesses by NMR, InsightMR portfolio is ideal for both industrial and academic scientists studying, optimizing and controlling reactions. InsightMR’s two components, a flow unit and dedicated software, enable online monitoring of (bio)chemical reactions in real-time under real process conditions.

Regulated Environments

GxP enabling kit with new software tools specially designed for state-of-the-art data integrity and compliance according to 21 CFR, part 11 principles.

Chemistry application for ChemLab

Bruker’s chemical analysis and metrology solutions accelerate the development of future chemical products and help ensure better product quality and performance.

NMR for Olive Oil Profiling

Strengthen your brand’s image and ensure your product’s quality and authenticity with NMR-based Olive Oil-Profiling

Analysis of Brucine on Fourier 80 Benchtop

Brucine is a naturally occurring alkaloid that contributes to the toxic effects of Nux-vomica seeds found in trees native to southern Asia. The Fourier 80 MHz benchtop NMR readily tackles investigations of substances such as brucine.

Thermodynamic and Kinetic Characterization of a Hydrolysis Reaction Using the Adjustable Temperature Feature of the Fourier 80

Benchtop Nuclear Magnetic Resonance (NMR) spectrometers are versatile tools for structure elucidation and verification, reaction monitoring, and quality control. In contrast to their larger, floor standing counterparts they are an order of magnitude less expensive in acquisition, have negligible operating costs, and require only minimal laboratory infrastructure.

NMR for Poloxamers/Polymers

This application note describes how Bruker’s FT-NMR benchtop spectrometer, the Fourier 80, was used to quantify the oxyethylene weight percentage in poloxamers.

Industry/Hygiene Solutions

Hand hygiene has been at the center of the global response to the COVID-19 pandemic, with alcohol-based sanitizers playing a key role. However, several reports indicate that hand sanitizer fraud is prevalent. Rapid testing methods such as benchtop Nuclear Magnetic Resonance (NMR) spectroscopy can determine the alcohol content or percentage volume (% vol) of hand sanitizers in seconds, preventing fraud.

All Fourier 80 related Application Notes:

Application Notes

Software

TopSpin

Bruker’s TopSpin^® software package for NMR data analysis and the acquisition and processing of NMR spectra.

GoScan

A push-button NMR software solution that guides users through easy-to-use dedicated workflows.

InsightMR

Monitor reactions, enhance reaction understanding, gain confidence when transferring processes from lab to plant. Learn more.

GxP NMR

GxP NMR enabling kit with new software tools specially designed for state-of-the-art data integrity and compliance according to 21 CFR, part 11 principles.

SPECIFICATIONS

Operating Frequency:	80 MHz (¹H) (Corresponds to 1.88 Tesla)
Nuclei selection:	The high performer: ¹H-only system with ¹H sensitivity of ≥ 240:1 or ≥ 220:1 when pulsed field gradient (PFG) incl. (1% ethyl benzene)
	The workhorse: ¹H/¹³C system with ¹H sensitivity of ≥ 180:1 or ≥ 160:1 when PFG incl. (1% ethyl benzene)
	The multi-talent: ¹H/¹³C\|¹⁹F system with sensitivity optimized for the X-channel, PFG incl.; sensitivity: ¹H: ≥ 110:1 (1% ethyl benzene) ¹³C: ≥ 35:1 (100% ethyl benzene) ¹⁹F: ≥ 110:1 (0.5% TFT in CDCl₃)
	The specialist: ¹H/X system with one dedicated X nucleus (⁷Li, ¹¹B, ¹³C, ²³Na, ²⁹Si, ³¹P, ¹¹⁹Sn, or ¹²⁹Xe), and sensitivity optimized for the X-channel, PFG incl; sensitivity: ¹H: ≥ 90:1 (1% ethyl benzene) X options (contact us for more): ⁷Li: ≥ 2000:1 (1 M LiBr in D₂O) ¹¹B: ≥ 45:1 (0.75 M boric acid in D₂O) ¹³C: ≥ 65:1 (100% EB) ²³Na: ≥ 65:1 (0.5 M NaCl in D₂O) ²⁹Si: ≥ 45:1 (100% HMDSO) ³¹P: ≥ 130:1 (0.485M TPP in Acetone-d6)
Gradient strength:	≥ 0.25 T/m (25 G/cm)
Adjustable temperature	25°C - 60°C*
Automation:	PAL RSI sample changer; up to 120 samples + 12 reference samples
¹H Resolution (@ 50/0.55/ 0.11% signal height) :	Standard: ≤ 0.4/ 15/ 30 Hz HD-Option: ≤ 0.3/ 10/ 15 Hz
Digital Lock:	External, no deuterated solvents needed
Sample Tubes:	standard 5mm diameter, 7’’-long NMR tubes: compatible with Young tubes
Dimensions:	~50 cm x 70 cm x 60 cm (Height x Width x Depth)
Weight:	~94 kg
Lab Temperature:	18-28°C; Measurements at sample temperature > 40°C: 18-25°C
Lab Infrastructure needed:	no liquid nitrogen or helium required no water cooling required power consumption typically <300 W power: 100 – 240 V, 50 – 60 Hz no additional venting required AT needs compressed air or nitrogen at 5 bar max.
	*Incoming supply gas temperature must be min.5°C lower than the target temperature