Superior accuracy

Unbeatable limit of quantitation


The EVOQ® triple quadrupole for liquid chromatography (LC-TQ) was designed for a singular purpose—to reliably quantify thousands of real samples in the fastest sample-to-report time possible.

Triple Quad MS

Game changer for routine multiple reaction monitoring (MRM) assays

Accuracy & precision
Together, these parameters measure the total error of the assay, resulting in an unbeatable LOQ in matrix as routine on the EVOQ® LC-TQ.
MRM method builder, designed by chromatographers, auto-fills MRM transition in intuitive workflow design.
Analyze thermally labile molecules at high flow rates with the vacuum insulated probe (VIP) heated electrospray probe.

True workflow design—easy to learn, intuitive to use

Today Bruker is pioneering the migration of technology from research to commercial laboratory. The EVOQ® Elite and EVOQ® Qube reflect this design philosophy and solve the hardware and software challenges faced by the quantitative analysis community

  • Workflow design - Simple, intuitive, powerful
    The daily laboratory routine faces constant demands, including following standards and regulations, meeting stringent timelines, and fulfilling various reporting requests. The powerful software suite for the EVOQ® LC-TQ series simplifies workflows from sample to report, with instrument and user interfaces that adapt to your needs.
  • Client-server based software – integrating instruments for high throughput and ease of use
    The software integrates acquisition and data handling together, and allows the installation to be tailored specifically to the laboratory’s needs. Whether this is one instrument at one station, or a centralized server with several mass spectrometers feeding data in from all over the world, the Bruker network maximizes  system uptime.
  • Libraries - User-created or commercial library support
    The EVOQ® GC-TQ gives users the freedom to create an unlimited number of libraries to share with partners around the world, which can be shared between different clients from one or more servers. The use of pre-determined libraries and databases commercially available in NIST format represents a substantial time saving.
  • MRM Method Builder - Designed by chromatographers
    The EVOQ® LC-TQ’s autofill function removes the need to know the MRM transition of an analyte. A simple drag-and-drop of the compound from the factory-installed compound library, which contains more than 3000 MRM transitions, lets the software set up the method and manage the TQ duty cycle.

The EVOQ® LC-TQ delivers MRM assays with exceptional sensitivity and accuracy

  • Easily obtain ultra-high sensitivity for small molecules and biomolecules as a result of the innovative interlaced quadrupole (IQ) dual ion funnel.
  • Confidently run matrix-rich samples on the robust orifice plate-based API interface.
  • Efficiently analyze thermally labile molecules at high flow rates with the vacuum insulated probe (VIP) heated electrospray probe.
  • Save time using exception-based data-review software that makes it easier to highlight chromatograms that do not meet preset method criteria.

Accuracy and Precision

The EVOQ® LC-TQ routinely achieves an unbeatable limit of quantitation (LOQ) in matrix.

While accuracy is the measure of the closeness of the experimental value of the actual amount of the target analyte in matrix (a measure of systematic bias), precision is how well the experimental values agree with each other (a measure of random error). Together these parameters measure the total error of the assay, which in turn determines the LOQ.

accuracy and precision

Key applications

  • Food Analysis and Testing
    Ideal for testing for pesticide and veterinary drug residues, and other contaminants in food products. The high MRM speed allows high throughput chromatography testing, delivering a wide scope of applications and unprecedented flexibility.
  • Environmental Analysis
    The MRM software databases allow the simple set up of methods to screen and quantify hundreds of compounds, even those detected in low amounts.
  • Forensic Toxicology
    Body fluids are amongst the toughest matrices for analysis. The EVOQ® GC-TQ series delivers sustained sensitivity and robustness to meet the unique challenges of forensic analysis, while minimizing maintenance downtime.
  • Targeted Metabolomics
    The software suite brings the EVOQ® GC-TQ system in line with Bruker’s well known instrumentation and software for Metabolomics and Phenomics investigations. Users can now integrate data from every Bruker instrument using the same workflows.